Publications – May 15, 2020

Biological Considerations in Scaling Up Therapeutic Cell Manufacturing
(Darshana S. Cherian, Tejasvini Bhuvan, Tracy S. P. Heng)

A homozygous variant in NDUFA8 is associated with developmental delay, microcephaly, and epilepsy due to mitochondrial complex I deficiency
(Formosa LE, Ryan MT)

The complexity of T cell-mediated penicillin hypersensitivity reactions
(Goh SJR, Tuomisto JEE, Purcell AW, Mifsud NA, Illing PT)

Migration of murine intestinal dendritic cell subsets upon intrinsic and extrinsic TLR3 stimulation
(O’Keeffe M)

Oocytes can efficiently repair DNA double-strand breaks to restore genetic integrity and protect offspring health
(Stringer JM, Winship A, Zerafa N, Wakefield M, Hutt K)

In-depth mining of the immunopeptidome of an acute myeloid leukemia cell line using complementary ligand enrichment and data acquisition strategies
(Pandey K, Mifsud NA, Lim Kam Sian TCC, Ayala R, Ramarathinam SH, Purcell AW)

In Pursuit of the triple Crown: mechanism-based pharmacodynamic modeling for the optimization of 3-drug combinations against KPC-Producing Klebsiella pneumoniae
(Li J)

Pharmacokinetics/pharmacodynamics of antipseudomonal bacteriophage therapy in rats: A Proof-of-Concept study
(Lin YW, Han ML, Zhao J, Chen K, Wang J, Li J)

A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease
(Ting YT, Kim HSK, Petersen J, Reid HH, Rossjohn J)

Interferon-β-induced miR-1 alleviates toxic protein accumulation by controlling autophagy (Nehammer C, Gopal S, Handley A, Ng L, Moreira P, Pocock R)

A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver T RM Cell-Mediated Immunity against Malaria in Mice
(Huang C, Tan PS, Tullett KM, Jones CM,  Purcell AW, La Gruta NL, Gras S, Lahoud MH, Schittenhelm RB, Caminschi I)

Ultra-high Field Diffusion Tensor Imaging identifies discrete patterns of concussive injury in the rodent brain
(Abraha HM, Panagiotopoulou O)

Polymyxin triple combinations against polymyxin-resistant, multidrug-resistant KPC-producing Klebsiella pneumoniae
(Aye SM, Yu H, Wang J, Chen K, Wickremasinghe H, Bergen PJ, Zhao J, Lin YW,Li J)

Imaging lipophilic regions in rodent brain tissue with halogenated BODIPY probes
(Gillespie-Jones K, Rajan R)

The Diiron Monooxygenase CmlA from Chloramphenicol Biosynthesis Allows Reconstitution of β-Hydroxylation during Glycopeptide Antibiotic Biosynthesis
(Kaniusaite M, Goode RJA, Schittenhelm RB, Cryle MJ)

The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function
(MacLachlan BJ, Pymm P, Illing PT, Purcell AW, Rossjohn J, Vivian JP)

Structure-Activity Relationship Study Reveals the Molecular Basis for Specific Sensing of Hydrophobic Amino Acids by the <i>Campylobacter jejuni</i> Chemoreceptor Tlp3
(Khan MF, Machuca MA, Rahman MM, Roujeinikova A)